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Diagnosis & Confirmatory Tests
A definitive diagnosis is reached by compiling clinical history, thorough physical examinations, and specific structural and fluid laboratory diagnostics.
Bloodwork Checklist
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RBC / HCT (Red Blood Cells)
Often low, indicating non-regenerative anemia. An HCT level below 15% is highly critical and requires urgent attention.
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WBC / Neutrophils
Typically elevated significantly, acting as a clear biological response to active tissue inflammation.
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Lymphocytes
Often low (Lymphopenia), reflecting a compromised or exhausted systemic cell-mediated immune response.
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Proteins & A:G Ratio
Characterized by elevated Globulin (inflammatory marker) and decreased Albumin. Ideally, we want the overall A:G ratio to rise toward 0.7 or higher during treatment progress.
CSF & Aqueous Humor Analysis
Cerebrospinal Fluid (brain/spine) and aqueous humor (eye) fluid panels reveal highly elevated protein levels and high nucleated cell counts, predominantly dominated by neutrophils.
Advanced RT-PCR Testing
Highly sensitive and specific when utilizing laboratory assays that target the FCoV 7b gene on extracted body fluid or affected tissue specimens.
Diagnostic MRI Imaging
Neurological assessments reveal vital structural modifications including marked meningeal contrast enhancement, ventriculomegaly (hydrocephalus), or cerebral swelling.