CureFIP™ GS-441524 Injectable 20mg/mla2

Description

CureFIP™ GS-441524 + B12 Injectable 20mg/ml

Antiviral Treatment With Integrated Cobalamin Support for Small Cats and Kittens

What This Product Is

CureFIP™ GS-441524 + B12 20mg/ml is a combined antiviral and nutritional support formulation containing GS-441524 at 20mg/ml and cyanocobalamin (Vitamin B12) at 50mcg/ml in a single injectable solution. It is designed for FIP treatment in cats weighing under 2.5 kg where secondary systemic complications — anaemia, neurological involvement, appetite suppression, or immune compromise — are present alongside the primary FIP diagnosis.

 

The antiviral component is identical to the standard CureFIP™ GS-441524 20mg/ml formulation. The addition of B12 does not alter GS-441524 concentration, dosing calculation, or antiviral mechanism. It adds a clinically meaningful layer of systemic support delivered through the same injection, eliminating the need for a separate B12 administration.

 

Why This Concentration: The Small Cat Precision Argument

In cats under 2.5 kg, high-concentration formulations produce injection volumes too small for reliable measurement. The 20mg/ml format ensures the daily GS-441524 dose can be drawn and administered accurately. This is the foundational reason for the 20mg/ml concentration — see the standard 20mg/ml product page for the full dosing precision rationale.

 

Why B12 Has Been Added

FIP is a systemic viral disease. By the time most cats are diagnosed, the feline infectious peritonitis virus (FIPV) has produced widespread inflammatory damage across multiple organ systems. The antiviral activity of GS-441524 addresses viral replication directly — but it does not immediately reverse the systemic damage already in progress. Many cats, particularly small cats and kittens whose physiological reserves are limited, present with one or more of the following secondary complications at diagnosis:

 

Anaemia FIPV-associated inflammation suppresses erythropoiesis — the production of red blood cells. Anaemic cats are lethargic, cold-intolerant, and have compromised oxygen delivery to tissues. Cobalamin is an essential cofactor in red blood cell synthesis. B12 at 50mcg/ml supports haematopoietic recovery alongside viral clearance.

 

Neurological involvement Dry (non-effusive) FIP and neurological FIP presentations involve central nervous system inflammation. Myelin sheath integrity — critical for nerve signal transmission — is partially B12-dependent. Cobalamin supplementation contributes to neurological recovery in affected cats, complementing the antiviral suppression of the underlying viral cause.

 

Appetite suppression and weight loss FIP cats frequently present with significant appetite loss, accelerating weight decline that is particularly dangerous in cats already under 2.5 kg. Cobalamin has a well-documented role in appetite pathway activation. B12 administration commonly produces observable improvements in appetite within the first days of treatment, supporting the nutritional intake necessary for recovery.

 

Immune system compromise Cobalamin is a cofactor in multiple immune system processes including lymphocyte proliferation. FIP-associated immune dysfunction is partially addressable through B12 supplementation alongside antiviral therapy.

 

Gastrointestinal dysfunction Some FIP presentations include GI involvement affecting nutrient absorption. B12 supports intestinal mucosal integrity and is itself absorbed through the GI tract — the injectable route in this formulation bypasses any absorption compromise entirely.

 

What B12 at 50mcg/ml Means Clinically

The 50mcg/ml concentration is formulated as adjunctive support — a clinically meaningful supplement dose delivered through the existing daily antiviral injection. It is not intended as a standalone therapeutic dose for severe B12 deficiency, which would require separate supplementation at different intervals and doses under veterinary guidance. If your cat has been diagnosed with primary B12 deficiency requiring therapeutic dosing, maintain the separate B12 protocol as directed by your veterinarian and inform our clinical team.

 

Indicated Cases

This formulation is most appropriate for:

• Kittens and small adult cats under 2.5 kg with FIP and confirmed or suspected anaemia
• Neurological FIP presentations in the small cat weight range
• Cats presenting with significant appetite loss or weight decline at diagnosis
• Cases where the owner or attending veterinarian wishes to consolidate antiviral and nutritional support into a single daily injection
• Cats with a history of B12-responsive conditions alongside a new FIP diagnosis

 

This Formulation Is Not the First Choice For

• Cats requiring therapeutic-dose B12 supplementation independently — maintain a separate B12 protocol as directed
• Cats over 2.5 kg — consider the 30mg/ml + B12 or 40mg/ml + B12 formulations
• Cases where the veterinarian has specifically indicated the non-B12 formulation

 

Concentration Selection Guide

Concentration	Primary Indication
20mg/ml + B12 (this product)	Cats under 2.5 kg with anaemia, neurological symptoms, or appetite loss
20mg/ml	Cats under 2.5 kg · Standard antiviral only
30mg/ml + B12	Cats 2.5–5 kg with secondary systemic complications
40mg/ml + B12	Cats over 5 kg, high-dose protocol with systemic support needs

 

Administration

Administer subcutaneously once daily. Dose is calculated in mg of GS-441524 per kg of body weight — the B12 component does not alter the dose calculation. Standard treatment duration is 84 consecutive days. Use the dosing calculator to determine the correct volume for your cat’s current weight. Do not adjust dose without veterinary guidance.